AESKULISA ELISA Test Kits

Rheumatology – Vasculitis – Hepatology – Gastroenterology – Myositis

The AESKUBLOTS® test line represents a variety of different immunoblots for an efficient sample testing of autoimmune and infectious diseases. Being coated with a plethora of specific antigens on one test strip, AESKUBLOTS® provide a complete diagnostic overview in a single test and are suitable for screening of autoimmune diseases as well as for cost-effective differential diagnosis.


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AUTOIMMUNITY Products  No FDA cleared products available in this section
Reference Description Test per kit Conjugate

4000 ANA-12 Pro 24 IgG

ANA-12 Pro (BLOT)

24 tests/kit

Conjugate: anti-human IgG HRP

Color-coded (yellow) test strips with cut-off and positive control.

Immunoblot for the qualitative detection of IgG antibodies against:

nucleosomes, dsDNA, histones, SmD1, U1-snRNP, SS-A/Ro60kD, SS-A/Ro52kD, SS-B/La, Scl-70, CENP-B, Jo-1 and ribosomal P protein (P0) in human serum or plasma.

AESKUBLOTS ANA-12 Pro is used for the differential diagnosis of systemic rheumatic diseases. The detection of autoantibodies in AESKUBLOTS with the corresponding speci?c antigens allows an easier and more reliable differentiation of speci?c ANAs (anti-nuclear antibodies). ANAs occur in active and inactive systemic lupus erythematosus (SLE), mixed connective tissue diseases (MCTD), scleroderma, Sjogren's syndrome and polymyositis.

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4001 ANA-17 Pro 24 IgG

ANA-17 Pro (BLOT)

24 tests/kit

Conjugate: anti-human IgG HRP

Color-coded (orange) test strips with cut-off and positive control.

Immunoblot for the qualitative detection of IgG antibodies against:

dsDNA, nucleosomes, histones, SmD1, PCNA, P0, SS-A/Ro60kD, SS-A/Ro52kD, SS-B/La, CENP-B, Scl-70, U1 snRNP, AMA M2, Jo-1, Pm-Scl, Ku and Mi-2 in human serum or plasma.

AESKUBLOTS ANA-17 Pro is used for the differential diagnosis of systemic rheumatic diseases. The detection of autoantibodies in AESKUBLOTS with the corresponding speci?c antigens allows an easier and more reliable differentiation of speci?c ANAs (anti-nuclear antibodies). ANAs occur in active and inactive systemic lupus erythematosus (SLE), mixed connective tissue diseases (MCTD), scleroderma, Sjogren's syndrome, primary biliary cirrhosis (PBC) and polymyositis. ANA-17 Pro antigens are ?tted on the test strip according to their relevance for the individual autoimmune disease (SLE, Sjogren's syndrome, CREST syndrome, scleroderma, MCTD, myositis, and PBC) for easier interpretation.

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4002 Vasculitis Pro 24 IgG

Vasculitis Pro (BLOT)

24 tests/kit

Conjugate: anti-human IgG HRP

Color-coded (purple) test strips with cut-off and positive control.

Immunoblot for the qualitative detection of IgG antibodies against:

PR3, MPO and GBM in human serum or plasma.

AESKUBLOTS Vasculitis Pro is used for the differential diagnosis of autoimmune vasculitis. Antibodies against proteinase 3 (PR3) and myeloperoxidase (MPO) belong to the group of anti-neutrophil cytoplasmic antibodies (ANCA), which have been described as an important marker in the differential diagnosis of autoimmune vasculitis. Anti-PR3 antibodies represent a speci?c serological marker for granulomatosis with polyangiitis (Wegener's) and could play a role in pathogenesis. Anti-MPO antibodies occur in idiopathic and vasculitis-associated rapidly progressive glomerulonephritis, they are found in up to 70% of microscopic polyangiitis, and up to 5-50% in the Churg-Strauss syndrome. The serological detection of circulating antibodies against glomerular basement membrane in the glomeruli (GBM) is the method of choice in diagnosis of Goodpasture's syndrome.

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4003 Myositis Pro 24 IgG

Myositis Pro (BLOT)

24 tests/kit

Conjugate: anti-human IgG HRP

Color-coded (blue) test strips with cut-off and positive control.

Immunoblot for the qualitative detection of IgG antibodies against:

Jo-1, Mi-2, Pm-Scl, U1-snRNP and Ku in human serum or plasma.

AESKUBLOTS Myositis Pro is designed to help in the diagnosis of poly- and dermatomyositis, as well as myositisassociated autoimmune diseases. Autoimmune myositis represents a heterogeneous group of acquired muscle diseases. Their main clinical and morphological characteristics are muscle weakness and in?ammatory in?ltration of skeletal muscles.

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4004 Liver Pro 24 IgG

Liver Pro (BLOT)

24 tests/kit

Conjugate: anti-human IgG HRP

Color-coded (brown) test strips with cut-off and positive control.

Immunoblot for the qualitative detection of IgG antibodies against:

AMA M2, Sp100, LKM1, gp210, LC1 and SLA in human serum or plasma.

AESKUBLOTS Liver Pro is used as an aid in the diagnosis of autoimmune liver diseases. The most important autoimmune liver diseases are autoimmune hepatitis (AIH) types 1-3, primary biliary cirrhosis (PBC) and a combination of both diseases, the Immunocholangiopathy. AIH is a chronic, progressive liver disease of unknown cause, which responds well to immunosuppressive therapy, however, being untreated it has a poor prognosis. The PBC is a chronic in?ammatory disease of the small and medium-size bile ducts. Undetected it can lead to liver cirrhosis. An early and reliable diagnosis is therefore of great importance.

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4005 Gastro Pro 24 IgA/IgG

Gastro Pro (BLOT)

24 tests/kit

Conjugate: anti-human IgA/IgG HRP

Color-coded (black) test strips with cut-off and positive control.

 

Immunoblot for the qualitative detection of IgA/IgG antibodies against:

Gliadin, Neo-tTG, mannan (ASCA), parietal cells and intrinsic factor-antigen.

 

AESKUBLOTS Gastro Pro is designed to assist in the diagnosis of celiac disease, pernicious anemia and Morbus Crohn. Each section of the gastro-intestinal tract can be affected by autoimmune gastrointestinal diseases. Often the disease is diagnosed years after the ?rst symptoms occurred and has a severe outcome in many cases. Celiac patients often have an IgA de?ciency. In order to avoid false-negative results, AESKUBLOTS Gastro Pro detects IgA and IgG antibodies.

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